The importance of treating otitis externa

Otitis externa (OE) is a common, debilitating condition affecting up to 1 in 5 dogs in their lifetime and is seen on a daily basis in first opinion practice.1,2

Otitis is always painful and usually pruritic and has been shown to affect both the quality of life of owners and their dogs who develop it.3 Whilst the development of otitis externa is not an emergency, it is a potentially urgent problem that could lead to significant welfare compromise if left untreated -

Otitis has been shown to have an impact on dogs’ sleep and playing behaviours, and cause their owners physical or emotional disturbances.3 Where otitis is not addressed adequately, a dramatic deterioration of the dog-owner relationship has been shown to occur, leading to low treatment compliance and the development of ear phobias in affected dogs.4 The key to therapy should be early intervention and based on recent quality of life studies, this should be with a veterinary directed treatment rather than an owner directed treatment.5

Neptra is a one dose solution licensed for the treatment of the most common pathogens seen in 70-80% of OE cases (Staphylococcus pseudintermedius and Malassezia pachydermatis).
Even if, under the current exceptional circumstances, it is not possible to perform cytology, then Neptra is an appropriate product to choose for most OE cases. It contains a first line antibiotic (florfenicol) which is not on the WHO list of critically important antibiotics, improving antibiotic stewardship, as well as an antifungal (terbinafine) and a potent corticosteroid (mometasone furoate). This highly potent, but “soft” corticosteroid acts rapidly and effectively at a local level to reduce inflammation within the ear canal, with minimal systemic absorption. Neptra improves comfort and there is no need for owners to treat their dog at home – reducing stress for everyone and improving compliance.

Dr Sue Paterson MA VetMB DVD DipECVD FRCVS, RCVS and European Specialist in Veterinary Dermatology

Have you heard?

There’s an easier way to treat otitis externa.

Introducing Neptra®

Neptra® is an effective new option for the treatment of acute canine otitis externa or acute exacerbations of recurrent otitis caused by mixed infections of susceptible strains of bacteria sensitive to florfenicol (Staphylococcus pseudintermedius) and fungi sensitive to terbinafine (Malassezia pachydermatis).

The ONLY first-line treatment available in ONE vet-administered dose.

Offering complete control over compliance in the treatment of otitis externa, Neptra removes the owner responsibility, stress and uncertainty of repeated at-home treatments.

Ideal for first-line use and effective against the most common pathogens* - associated with 70-80% of OE cases, make Neptra your first choice for OE treatment.

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Successful managementof otitis externa

Canine otitis externa (OE) is common, affecting up to 1 in 5 dogs1 visiting your practice.

After otoscopic examination, successful management of OE requires cytology to be performed. When Malassezia pachydermatis and Staphylococcus pseudintermedius are identified reach for Neptra®.

Most vets will have experienced compliance issues with at-home, multiple dose OE treatments – something that Neptra's one dose, administered-by-the-vet formulation provides a solution for.

Neptra should not be reserved for 'difficult cases'. With its suitability for first-line use, proven efficacy against the most common pathogens associated with OE and elimination of owner compliance issues, make Neptra your first choice for treating OE.


Neptra® – a unique combination

Neptra® contains a unique combination of three active ingredients that work together to be effective against the most common pathogens associated with otitis externa, as well as providing potent anti-inflammatory and anti-pruritic action, giving welcome relief from the discomfort of OE.

The single-dose, easier solution for otitis externa

The single-dose, easier solution for otitis externa

NEW to the UK

Neptra® is the ONLY first-line treatment available in ONE vet-administered dose for canine otitis externa.

Its innovative formulation provides lasting action after one application, making the treatment of otitis externa easier for everyone.

Hear from the experts

Hear from the experts Watch Video

Otitis externa

with Dr Sarah Warren, BVetMed MSc CertVD MRCVS, President of BVDSG

Dr Sarah Warren details the challenges involved in treating otitis externa in dogs. There are many primary, predisposing and perpetuating factors which should be considered when managing the disease as these lead to or prevent resolution of secondary infection. Cytology is a useful, inexpensive tool that can be performed in house so you can have confidence knowing what infections you are treating – 70-80% of the time these are Staphylococcus pseudintermedius and Malassezia pachydermatis. As we know, owner compliance can often be poor with multidose treatments and Sarah discusses this.

Hear from the experts Watch Video

Neptra® - for first line use

with Dr Kenneth W. Kwochka, DVM, DACVD, President of the World Association of Dermatology

Dr. Ken Kwochka discusses why Neptra is an ideal first line product for the majority of Otitis externa cases which present with Staphylococcus pseudintermedius and Malassezia pachydermatis.

You've heard, have your clients?

We have a range of materials available to help you educate pet owners on otitis externa, and treatment with Neptra® once prescribed.

You've heard, have your clients?

* Staphylococcus pseudintermedius and Malassezia pachydermatis.

  1. Angus J. C. Vet Clinics of North America: Small Animal Practice. 2004 Mar;34(2):411-24.
  2. Hill PB, Lo A, Eden CA, Huntley S, Morey V, Ramsey S, et al. Survey of the prevalence, diagnosis and treatment of dermatological conditions in small animals in general practice. Vet Rec. 2006;158(16):533-9.
  3. Jamet J-F, Marignac G, Petit JY. Prospective study of the effect of otitis externa before and after treatment on 20 owners' assessment of their and their dog's quality of life Vet Dermatol. 2016;27:45 (abstract)
  4. Boda C, Liege P, Reme CA. Evaluation of owner compliance with topical treatment of acute otitis externa in dogs: a comparative study of two auricular formulations. Int J Appl Res Vet Med. 2011;9:157-65.
  5. Noli C, Sartori R, Cena T. Impact of a terbinafine-florfenicol-betamethasone acetate otic gel on the quality of life of dogs with acute otitis externa and their owners. Vet Dermatol. 2017;28(4):386-e90.
  6. Dog Owner Compliance Evaluation, June 2019, n=2000 dog owners from FR/IT/ES/DE/NL/BE/UK/AU
  7. World Health Organization (WHO). (2011). Critically important antimicrobials for human medicine. 3rd Revision. Available at: Accessed March 20, 2019.
  8. Spada, F. et al. (2018) Australasian Journal of Dermatology 59(3): e168-e174
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